Evaluation

Evaluation - Our expertise, including our extensive experience with highly refined animal models for cancer and infectious diseases, allows us to evaluate proteins extremely efficiently.

Product characterization - Whether we produce a protein for a client or the client brings a protein to us which they have created, we have exceptional expertise to analyze its physical and functional properties. This analysis can include:

· Product properties

· Correct molecular weight

· Assembly

· Glycosylation

· Antigen biding

· Antibody effector functions including Complement activation, Fc receptor binding, and antibody dependent cellular cytotoxicity

· Non-antibody effector functions of protein fusions including receptor binding, proliferation, cytotoxic activity, apoptosis and chemotactic activity

Pre-clinical (in vivo) studies - For any protein, including antibodies and antibody protein fusions we can provide highly reliable pre-clinical studies including:

· Half-life

· Biodistribution

· In vivo stability

· Toxicity

· Efficacy including tumor targeting, anti-tumor activity and anti-infectuous activity

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